The Environmental Protection Agency (EPA) of the United States formally approved two end-use plant growth regulator products and a novel active ingredient, metamitron, on March 11, 2025. To maximize fruit output, these products are approved for use on apple and pear trees. 

Metamitron: A Key Tool for Fruit Growth Optimization

During the post-bloom phases, a chemical thinning agent called metamitron is sprayed to tree foliage. The remaining fruits can absorb more nutrients due to the quick reduction of extra fruit set, which encourages larger and higher-quality fruits. The EPA emphasized that this technology will help farmers support sustainable agricultural practices, reduce the hazards of overcropping to plant health, and precisely regulate yields.

maximize the production of fruit.

Safety Assessment: No Significant Risks to Health or Ecology

Metamitron underwent extensive ecological and human health risk assessments by the EPA under the Endangered Species Act (ESA). The chemical is safe for human health when taken as prescribed, according to the results. Further confirming Metamitron’s ecological safety, the EPA determined that its application on apple and pear trees won’t negatively impact endangered species or their habitats following an informal conversation with the U.S. Fish and Wildlife Service (FWS). 

Label Innovation: Enhancing Readability and Usability

In response to industry concerns with confusing pesticide labels and difficult-to-locate important information, EPA launched a structured labeling program in partnership with the Weed Science Society of America (WSSA) and registrant ADAMA North America. As pilot examples, the two recently approved end-use labels greatly improve user experience by using a consistent structure to classify important elements like Usage Instructions, Safety Warnings, and Environmental Precautions.

Conclusion

A significant step toward open and uniform pesticide management has been taken with the EPA’s approval of Metamitron and associated labeling changes. This decision not only meets growers’ pressing need for effective production solutions but also promotes agricultural sustainability through scientifically grounded ecological safeguards by fusing cutting-edge agronomic technologies with approachable regulatory frameworks.

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